[cs_content][cs_section bg_image=”https://tscireland.org/wp-content/uploads/2018/01/lung_banner.jpg” parallax=”false” separator_top_type=”none” separator_top_height=”50px” separator_top_angle_point=”50″ separator_bottom_type=”none” separator_bottom_height=”50px” separator_bottom_angle_point=”50″ _order=”0″ class=”cs-hide-sm cs-hide-xs” style=”margin: 0px;padding: 45px 0px;”][cs_row inner_container=”true” marginless_columns=”false” style=”margin: 0px auto;padding: 0px;”][cs_column fade=”false” fade_animation=”in” fade_animation_offset=”45px” fade_duration=”750″ type=”1/1″ class=”cs-ta-center” style=”padding: 0px;”][x_custom_headline level=”h2″ looks_like=”h2″ accent=”false” class=”cs-ta-center mtn, mbn” style=”color: hsl(0, 0%, 100%);font-style: italic;”]Supporting Each Other[/x_custom_headline][x_custom_headline level=”h2″ looks_like=”h1″ accent=”false” class=”cs-ta-center mtn” style=”color: hsl(0, 0%, 100%);”]TSC Ireland[/x_custom_headline][x_button shape=”pill” size=”large” block=”false” circle=”false” icon_only=”false” href=”/contact” title=”” target=”” info=”none” info_place=”top” info_trigger=”hover” info_content=””]Contact Us[x_icon type=”lightbulb-o” class=”mvn mls mrn”][/x_button][/cs_column][/cs_row][/cs_section][cs_section bg_image=”https://tscireland.org/wp-content/uploads/2018/01/lung_mobile.jpg” parallax=”false” separator_top_type=”none” separator_top_height=”50px” separator_top_angle_point=”50″ separator_bottom_type=”none” separator_bottom_height=”50px” separator_bottom_angle_point=”50″ class=”cs-hide-xl cs-hide-lg cs-hide-md” style=”margin: 0px;padding: 0px 0px 20px;”][cs_row inner_container=”true” marginless_columns=”false” style=”margin: 0px auto;padding: 0px;”][cs_column fade=”false” fade_animation=”in” fade_animation_offset=”45px” fade_duration=”750″ type=”1/1″ class=”cs-ta-center” style=”padding: 0px;”][x_custom_headline level=”h2″ looks_like=”h2″ accent=”false” class=”cs-ta-center mtn, mbn” style=”color: hsl(0, 0%, 100%);font-style: italic;”]Supporting Each Other[/x_custom_headline][x_custom_headline level=”h2″ looks_like=”h1″ accent=”false” class=”cs-ta-center mtn” style=”color: hsl(0, 0%, 100%);”]TSC Ireland[/x_custom_headline][x_button shape=”pill” size=”large” block=”false” circle=”false” icon_only=”false” href=”#” title=”” target=”” info=”none” info_place=”top” info_trigger=”hover” info_content=””]Contact Us[x_icon type=”lightbulb-o” class=”mvn mls mrn”][/x_button][/cs_column][/cs_row][/cs_section][cs_element_section _id=”23″][cs_element_row _id=”24″][cs_element_column _id=”25″][x_custom_headline level=”h2″ looks_like=”h3″ accent=”false”]Lung Involvement[/x_custom_headline][/cs_element_column][/cs_element_row][cs_element_row _id=”32″][cs_element_column _id=”33″] [/cs_element_column][cs_element_column _id=”34″][cs_text _order=”0″]The three main pulmonary lesions found in tuberous sclerosis complex (TSC) are lymphangioleiomyomatosis (LAM), multifocal micronodular pneumocyte hyperplasia, and clear cell tumor of the lung. LAM is the most common. The average age of onset is 32–34 years of age, and lung involvement is essentially, although not exclusively, a manifestation of TSC in women.[/cs_text][cs_text class=”mtm”]The first symptoms of lung involvement in an individual with TSC may be shortness of breath after mild exercise, spontaneous pneumothorax, or coughing. Progression to pulmonary failure may develop, but not usually until the third or fourth decade of life, if at all. Pulmonary involvement in TSC can be severe, and some individuals will require lung transplantation.[/cs_text][/cs_element_column][/cs_element_row][cs_element_row _id=”41″][cs_element_column _id=”42″][cs_text _order=”0″ class=”ptl”]Recent studies have shown that many women with TSC have minor, asymptomatic lung involvement. The Consensus Conference Panel on Lung Involvement recommended that female patients should have a chest CT scan (not an x-ray) sometime before age 18 or at the time of diagnosis for women older than 18. A CT scan of the lung is superior to an X-ray because the early signs of lung involvement may easily be missed on an X-ray. If pulmonary involvement is noted, the individual should be monitored closely and should have repeated chest CT scans as needed.[/cs_text][/cs_element_column][/cs_element_row][/cs_element_section][cs_element_section _id=”49″][cs_element_row _id=”50″][cs_element_column _id=”51″][x_button type=”real” shape=”rounded” size=”x-large” block=”false” circle=”false” icon_only=”false” href=”/donate” title=”” target=”” info=”none” info_place=”top” info_trigger=”hover” info_content=”” class=”mtl mbl”]Donate[x_icon type=”eur” class=”mvn mls mrn”][/x_button][cs_text class=”mbl”]
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find a cure for TSC
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[/cs_text][/cs_element_column][/cs_element_row][/cs_element_section][cs_element_section _id=”61″][cs_element_row _id=”62″][cs_element_column _id=”63″][cs_text]Pulmonary involvement in TSC can be severe, even fatal. Recently, tamoxifen and progesterone have been used to treat pulmonary TSC with encouraging results. Any individual with TSC with lung involvement should see a pulmonologist who is knowledgeable about LAM.[/cs_text][/cs_element_column][/cs_element_row][/cs_element_section][/cs_content]
